The CHRNA3 rs578776 variant is associated with an intrinsic reward sensitivity deficit in smokers

The CHRNA3 rs578776 variant is associated with an intrinsic reward sensitivity deficit in smokers

A compromised brain reward system has been postulated as a key feature of drug dependence. We examined whether several polymorphisms of genes found to regulate nicotinic acetylcholine receptor (nAChR) and dopamine (DA) expression were related to an intrinsic reward sensitivity (IRS) deficit we previ...

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Bibliographic Details
Main Authors: Jason D. Robinson, Francesco eVersace, Cho Y. Lam, Jennifer A. Minnix, Jeffrey M. Engelmann, Yong eCui, Maher eKaram-Hage, Sanjay S. Shete, Gail E. Tomlinson, Tina T.-L. Chen, David W. Wetter, Charles E. Green, Paul M. Cinciripini
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Psychiatry
Subjects:
Genetics
Nicotine
Smoking Cessation
Addiction
ERP
Cluster analysis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00114/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00114/full

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