Critical role of deadenylation in regulating poly(A) rhythms and circadian gene expression.

The mammalian circadian clock is deeply rooted in rhythmic regulation of gene expression. Rhythmic transcriptional control mediated by the circadian transcription factors is thought to be the main driver of mammalian circadian gene expression. However, mounting evidence has demonstrated the importan...

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Bibliographic Details
Main Authors: Xiangyu Yao, Shihoko Kojima, Jing Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007842