The neoepitope landscape in pediatric cancers

The neoepitope landscape in pediatric cancers

Abstract Background Neoepitopes derived from tumor-specific somatic mutations are promising targets for immunotherapy in childhood cancers. However, the potential for such therapies in targeting these epitopes remains uncertain due to a lack of knowledge of the neoepitope landscape in childhood canc...

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Bibliographic Details
Main Authors: Ti-Cheng Chang, Robert A. Carter, Yongjin Li, Yuxin Li, Hong Wang, Michael N. Edmonson, Xiang Chen, Paula Arnold, Terrence L. Geiger, Gang Wu, Junmin Peng, Michael Dyer, James R. Downing, Douglas R. Green, Paul G. Thomas, Jinghui Zhang
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Genome Medicine
Subjects:
Epitopes
Pediatric cancer
Immunotherapy
Gene fusions
Online Access:http://link.springer.com/article/10.1186/s13073-017-0468-3

Internet

http://link.springer.com/article/10.1186/s13073-017-0468-3

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