The Ribosomal Protein L28 Gene Induces Sorafenib Resistance in Hepatocellular Carcinoma

BackgroundSorafenib is the first molecular-targeted drug for the treatment of advanced hepatocellular carcinoma (HCC). However, its treatment efficiency decreases after a short period of time because of the development of drug resistance. This study investigates the role of key genes in regulating s...

Full description

Bibliographic Details
Main Authors: Yi Shi, Xiaojiang Wang, Qiong Zhu, Gang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.685694/full