Pan-cancer chromatin analysis of the human vtRNA genes uncovers their association with cancer biology [version 2; peer review: 1 approved, 2 approved with reservations]

Background: The vault RNAs (vtRNAs) are a class of 84-141-nt eukaryotic non-coding RNAs transcribed by RNA polymerase III, associated to the ribonucleoprotein complex known as vault particle. Of the four human vtRNA genes, vtRNA1-1, vtRNA1-2 and vtRNA1-3, clustered at locus 1, are integral component...

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Bibliographic Details
Main Authors: Rafael Sebastián Fort, María Ana Duhagon
Format: Article
Language:English
Published: F1000 Research Ltd 2021-06-01
Series:F1000Research
Online Access:https://f1000research.com/articles/10-182/v2