Pan-cancer chromatin analysis of the human vtRNA genes uncovers their association with cancer biology [version 2; peer review: 1 approved, 2 approved with reservations]
Background: The vault RNAs (vtRNAs) are a class of 84-141-nt eukaryotic non-coding RNAs transcribed by RNA polymerase III, associated to the ribonucleoprotein complex known as vault particle. Of the four human vtRNA genes, vtRNA1-1, vtRNA1-2 and vtRNA1-3, clustered at locus 1, are integral component...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2021-06-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/10-182/v2 |