CTLA-4 promotes lymphoma progression through tumor stem cell enrichment and immunosuppression

The recurrence rate of lymphoma is very high, and tumor stem cells may be an important mechanism. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) can inhibit antitumor immunity and promote cancer progression, but its role and mechanism in lymphoma are still unclear. Here we collected lymphoma t...

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Bibliographic Details
Main Authors: Chen Yan, Li Meng, Cao Jian, Cai Guohong, Li Xiantao, Liu Yuejiao, Chen Wen
Format: Article
Language:English
Published: De Gruyter 2021-09-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2021-0094