Prevalence and clinical implications of germline predisposition gene mutations in patients with acute myeloid leukemia

Abstract Acute myeloid leukemia (AML) is one of the most common types of leukemia. With the recent advances in sequencing technology and the growing body of knowledge on the genetics of AML, there is increasing concern about cancer predisposing germline mutations as well as somatic mutations. As fam...

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Bibliographic Details
Main Authors: Borahm Kim, Woobin Yun, Seung-Tae Lee, Jong Rok Choi, Keon Hee Yoo, Hong Hoe Koo, Chul Won Jung, Sun Hee Kim
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-71386-z