Selective blockade of trypanosomatid protein synthesis by a recombinant antibody anti-Trypanosoma cruzi P2β protein.

The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The single chain recombinant antibody C5 (scFv C5) directed against the C-terminal region of the Trypanosoma cruzi P2β protein (TcP2β) recognizes...

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Bibliographic Details
Main Authors: Maximiliano Juri Ayub, Benson Nyambega, Leandro Simonetti, Tomas Duffy, Silvia A Longhi, Karina A Gómez, Johan Hoebeke, Mariano J Levin, Cristian R Smulski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22570698/?tool=EBI