Plasmin Generation Potential and Recanalization in Acute Ischaemic Stroke; an Observational Cohort Study of Stroke Biobank Samples

Plasmin Generation Potential and Recanalization in Acute Ischaemic Stroke; an Observational Cohort Study of Stroke Biobank Samples

Rationale: More than half of patients who receive thrombolysis for acute ischaemic stroke fail to recanalize. Elucidating biological factors which predict recanalization could identify therapeutic targets for increasing thrombolysis success.Hypothesis: We hypothesize that individual patient plasmin...

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Bibliographic Details
Main Authors: Thomas Lillicrap, Charithani B. Keragala, Dominik F. Draxler, Jilly Chan, Heidi Ho, Stevi Harman, Be'eri Niego, Elizabeth Holliday, Christopher R. Levi, Carlos Garcia-Esperon, Neil Spratt, Prajwal Gyawali, Andrew Bivard, Mark W. Parsons, Joan Montaner, Alejandro Bustamante, Israel Fernandez Cadenas, Geoffrey Cloud, Jane M. Maguire, Lisa Lincz, Timothy Kleinig, John Attia, Simon Koblar, Monica Anne Hamilton-Bruce, Philip Choi, Bradford B. Worrall, Robert L. Medcalf
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neurology
Subjects:
acute stroke therapy
fibrinolysis
rtPA
thrombolysis
plasmin
stroke
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.589628/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2020.589628/full

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