BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development
Notch signaling plays a crucial role in controling the proliferation and differentiation of stem and progenitor cells during embryogenesis or organogenesis, but its regulation is incompletely understood. BLOS2, encoded by the Bloc1s2 gene, is a shared subunit of two lysosomal trafficking complexes,...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/18108 |