Mapping Gene Regulatory Networks in Drosophila Eye Development by Large-Scale Transcriptome Perturbations and Motif Inference

Genome control is operated by transcription factors (TFs) controlling their target genes by binding to promoters and enhancers. Conceptually, the interactions between TFs, their binding sites, and their functional targets are represented by gene regulatory networks (GRNs). Deciphering in vivo GRNs u...

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Bibliographic Details
Main Authors: Delphine Potier, Kristofer Davie, Gert Hulselmans, Marina Naval Sanchez, Lotte Haagen, Vân Anh Huynh-Thu, Duygu Koldere, Arzu Celik, Pierre Geurts, Valerie Christiaens, Stein Aerts
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714010043