Vitamin D Deficiency Aggravates the Renal Features of Moderate Chronic Kidney Disease in 5/6 Nephrectomized Rats

Vitamin D Deficiency Aggravates the Renal Features of Moderate Chronic Kidney Disease in 5/6 Nephrectomized Rats

The pathogenesis of chronic kidney disease (CKD) involves a very complex interaction between hemodynamic and inflammatory processes, leading to glomerular/vascular sclerosis, and fibrosis formation with subsequent evolution to end-stage of renal disease. Despite efforts to minimize the progression o...

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Bibliographic Details
Main Authors: Ana Carolina de Bragança, Daniele Canale, Janaína Garcia Gonçalves, Maria Heloisa Massola Shimizu, Antonio Carlos Seguro, Rildo Aparecido Volpini
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Medicine
Subjects:
chronic kidney disease
vitamin D deficiency
fibrosis
inflammation
5/6 nephrectomy
experimental model
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2018.00282/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2018.00282/full

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