High Glucose Induces Mouse Mesangial Cell Overproliferation via Inhibition of Hydrogen Sulfide Synthesis in a TLR-4-Dependent Manner

High Glucose Induces Mouse Mesangial Cell Overproliferation via Inhibition of Hydrogen Sulfide Synthesis in a TLR-4-Dependent Manner

Background/Aims: Overproliferation of mesangial cells was believed to play an important role in the progress of diabetic nephropathy, one of the primary complications of diabetes. Hydrogen sulfide (H2S), a well-known and pungent gas with the distinctive smell of rotten eggs, was discovered to play a...

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Bibliographic Details
Main Authors: Tao Ding, Wei Chen, Juan Li, Jiarong Ding, Xiaobin Mei, Haiyan Hu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Hydrogen sulfide
High glucose
Mesangial cells
TLR4
Online Access:http://www.karger.com/Article/FullText/461483

Internet

http://www.karger.com/Article/FullText/461483

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