Detection of mutations in the rpoB gene of rifampicin-resistant Mycobacterium tuberculosis strains inhibiting wild type probe hybridization in the MTBDR plus assay by DNA sequencing directly from clinical specimens

Abstract Background The potential of genetic testing for rapid and accurate diagnosis of drug-resistant Mycobacterium tuberculosis strains is vital for efficient treatment and reduction in dissemination. MTBDR plus assays rapidly detect mutations related to drug resistance and wild type sequences al...

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Bibliographic Details
Main Authors: Pallavi Sinha, G. N. Srivastava, Rajneesh Tripathi, Mukti Nath Mishra, Shampa Anupurba
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Microbiology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12866-020-01967-5