Investigation of the Potential of Nebivolol Hydrochloride-Loaded Chitosomal Systems for Tissue Regeneration: In Vitro Characterization and In Vivo Assessment

Investigation of the Potential of Nebivolol Hydrochloride-Loaded Chitosomal Systems for Tissue Regeneration: In Vitro Characterization and In Vivo Assessment

In this study, we evaluated the synergistic effect of nebivolol hydrochloride (NVH), a third-generation beta-blocker and NO donor drug, and chitosan on the tissue regeneration. Ionic gelation method was selected for the preparation of NVH-loaded chitosomes using chitosan lactate and sodium tripolyph...

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Bibliographic Details
Main Authors: Noha Ibrahim Elsherif, Abdulaziz Mohsen Al-Mahallawi, Abdelfattah Ahmed Abdelkhalek, Rehab Nabil Shamma
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
nebivolol hydrochloride
wound healing
tissue regeneration
chitosan lactate
chitosomes
Online Access:https://www.mdpi.com/1999-4923/13/5/700

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https://www.mdpi.com/1999-4923/13/5/700

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