Elevated β1-Adrenergic Receptor Autoantibody Levels Increase Atrial Fibrillation Susceptibility by Promoting Atrial Fibrosis

Elevated β1-Adrenergic Receptor Autoantibody Levels Increase Atrial Fibrillation Susceptibility by Promoting Atrial Fibrosis

ObjectiveBeta 1-adrenergic receptor autoantibodies (β1ARAbs) have been identified as a pathogenic factor in atrial fibrillation (AF), but the underlying pathogenetic mechanism is not well understood. We assessed the hypothesis that elevated β1ARAb levels increase AF susceptibility by promoting atria...

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Bibliographic Details
Main Authors: Luxiang Shang, Ling Zhang, Mengjiao Shao, Min Feng, Jia Shi, Zhenyu Dong, Qilong Guo, Jiasuoer Xiaokereti, Ran Xiang, Huaxin Sun, Xianhui Zhou, Baopeng Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Physiology
Subjects:
atrial fibrillation
β1-adrenergic receptor autoantibody
atrial fibrosis
circulating fibrosis biomarker
autoimmune
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00076/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00076/full

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