Anti-Malarial and Anti-Lipid Peroxidation Activities of Deferiprone-Resveratrol Hybrid in <i>Plasmodium berghei</i>-Infected Mice

Anti-Malarial and Anti-Lipid Peroxidation Activities of Deferiprone-Resveratrol Hybrid in <i>Plasmodium berghei</i>-Infected Mice

Iron is essential for all organisms including fast-dividing malarial parasites. Inversely, iron chelators can inhibit parasite growth through the inhibition of DNA synthesis and can ameliorate oxidative cell damage. Deferiprone (DFP)-resveratrol (RVT) hybrid (DFP-RVT) is a lipophilic anti-oxidative,...

Full description

Bibliographic Details
Main Authors: Hataichanok Chuljerm, Supawadee Maneekesorn, Voravuth Somsak, Yongmin Ma, Somdet Srichairatanakool, Pimpisid Koonyosying
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biology
Subjects:
iron chelator
lipid peroxidation
malaria
<i>Plasmodium</i>
antioxidant
Online Access:https://www.mdpi.com/2079-7737/10/9/911

Internet

https://www.mdpi.com/2079-7737/10/9/911

Similar Items