NOTCH3 expression is linked to breast cancer seeding and distant metastasis

NOTCH3 expression is linked to breast cancer seeding and distant metastasis

Abstract Background Development of distant metastases involves a complex multistep biological process termed the invasion-metastasis cascade, which includes dissemination of cancer cells from the primary tumor to secondary organs. NOTCH developmental signaling plays a critical role in promoting epit...

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Bibliographic Details
Main Authors: Alexey A. Leontovich, Mohammad Jalalirad, Jeffrey L. Salisbury, Lisa Mills, Candace Haddox, Mark Schroeder, Ann Tuma, Maria E. Guicciardi, Luca Zammataro, Mario W. Gambino, Angela Amato, Aldo Di Leonardo, James McCubrey, Carol A. Lange, Minetta Liu, Tufia Haddad, Matthew Goetz, Judy Boughey, Jann Sarkaria, Liewei Wang, James N. Ingle, Evanthia Galanis, Antonino B. D’Assoro
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Metastasis
Chromosomal instability
Centrosome amplification
Tumor stemness
Online Access:http://link.springer.com/article/10.1186/s13058-018-1020-0

Internet

http://link.springer.com/article/10.1186/s13058-018-1020-0

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