Suppression of La antigen exerts potential antiviral effects against hepatitis A virus.

BACKGROUND:Despite the development and availability of hepatitis A virus (HAV) vaccine, HAV infection is still a major cause of acute hepatitis that occasionally leads to fatal liver disease. HAV internal ribosomal entry-site (IRES) is one of the attractive targets of antiviral agents against HAV. T...

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Bibliographic Details
Main Authors: Xia Jiang, Tatsuo Kanda, Shuang Wu, Shingo Nakamoto, Kengo Saito, Hiroshi Shirasawa, Tomoko Kiyohara, Koji Ishii, Takaji Wakita, Hiroaki Okamoto, Osamu Yokosuka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4084951?pdf=render