Phosphocreatine interacts with phospholipids, affects membrane properties and exerts membrane-protective effects.

A broad spectrum of beneficial effects has been ascribed to creatine (Cr), phosphocreatine (PCr) and their cyclic analogues cyclo-(cCr) and phospho-cyclocreatine (PcCr). Cr is widely used as nutritional supplement in sports and increasingly also as adjuvant treatment for pathologies such as myopathi...

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Main Authors: Malgorzata Tokarska-Schlattner, Raquel F Epand, Flurina Meiler, Giorgia Zandomeneghi, Dietbert Neumann, Hans R Widmer, Beat H Meier, Richard M Epand, Valdur Saks, Theo Wallimann, Uwe Schlattner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422282?pdf=render