Synergistic Antivascular and Antitumor Efficacy with Combined Cediranib and SC6889 in Intracranial Mouse Glioma.

Synergistic Antivascular and Antitumor Efficacy with Combined Cediranib and SC6889 in Intracranial Mouse Glioma.

Prognosis remains extremely poor for malignant glioma. Targeted therapeutic approaches, including single agent anti-angiogenic and proteasome inhibition strategies, have not resulted in sustained anti-glioma clinical efficacy. We tested the anti-glioma efficacy of the anti-angiogenic receptor tyrosi...

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Bibliographic Details
Main Authors: Merryl R Lobo, Ayaka Kukino, Huong Tran, Matthias C Schabel, Charles S Springer, G Yancey Gillespie, Marjorie R Grafe, Randall L Woltjer, Martin M Pike
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4672903?pdf=render

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http://europepmc.org/articles/PMC4672903?pdf=render

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