Synergistic Antivascular and Antitumor Efficacy with Combined Cediranib and SC6889 in Intracranial Mouse Glioma.
Prognosis remains extremely poor for malignant glioma. Targeted therapeutic approaches, including single agent anti-angiogenic and proteasome inhibition strategies, have not resulted in sustained anti-glioma clinical efficacy. We tested the anti-glioma efficacy of the anti-angiogenic receptor tyrosi...
Main Authors: | Merryl R Lobo, Ayaka Kukino, Huong Tran, Matthias C Schabel, Charles S Springer, G Yancey Gillespie, Marjorie R Grafe, Randall L Woltjer, Martin M Pike |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4672903?pdf=render |
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