Paradoxical Roles of Tumour Necrosis Factor-Alpha in Prostate Cancer Biology

Tumour necrosis factor (TNF) is a pleiotropic cytokine with dual roles in cancer biology including prostate cancer (PCa). On the one hand, there is evidence that it stimulates tumour angiogenesis, is involved in the initiation of PCa from an androgen-dependent to a castrate resistant state, plays a...

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Bibliographic Details
Main Authors: Brian W. C. Tse, Kieran F. Scott, Pamela J. Russell
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/2012/128965