Genome-scale validation of deep-sequencing libraries.

Chromatin immunoprecipitation followed by high-throughput (HTP) sequencing (ChIP-seq) is a powerful tool to establish protein-DNA interactions genome-wide. The primary limitation of its broad application at present is the often-limited access to sequencers. Here we report a protocol, Mab-seq, that g...

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Bibliographic Details
Main Authors: Dominic Schmidt, Rory Stark, Michael D Wilson, Gordon D Brown, Duncan T Odom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2577887?pdf=render