Changes in circulating cell-free nuclear DNA and mitochondrial DNA of patients with adolescent idiopathic scoliosis

Changes in circulating cell-free nuclear DNA and mitochondrial DNA of patients with adolescent idiopathic scoliosis

Abstract Background Adolescent idiopathic scoliosis (AIS) which characterized by complex three-dimensional deformity of spine has been difficult to cure because of the unknown etiopathology and uncertainty of progression. Nowadays, circulating cell-free (ccf) DNA was found to be a potential biomarke...

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Bibliographic Details
Main Authors: Jiong Li, Longjie Wang, Guanteng Yang, Yunjia Wang, Chaofeng Guo, Shaohua Liu, Qile Gao, Hongqi Zhang
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Musculoskeletal Disorders
Subjects:
Adolescent idiopathic scoliosis
Circulating cell-free nuclear DNA
Circulating cell-free mitochondrial DNA
Sex differences
Lenke types
Online Access:http://link.springer.com/article/10.1186/s12891-019-2869-5

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http://link.springer.com/article/10.1186/s12891-019-2869-5

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