A systematic analysis of cell cycle regulators in yeast reveals that most factors act independently of cell size to control initiation of division.

A systematic analysis of cell cycle regulators in yeast reveals that most factors act independently of cell size to control initiation of division.

Upstream events that trigger initiation of cell division, at a point called START in yeast, determine the overall rates of cell proliferation. The identity and complete sequence of those events remain unknown. Previous studies relied mainly on cell size changes to identify systematically genes requi...

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Bibliographic Details
Main Authors: Scott A Hoose, Jeremy A Rawlings, Michelle M Kelly, M Camille Leitch, Qotaiba O Ababneh, Juan P Robles, David Taylor, Evelyn M Hoover, Bethel Hailu, Kayla A McEnery, S Sabina Downing, Deepika Kaushal, Yi Chen, Alex Rife, Kirtan A Brahmbhatt, Roger Smith, Michael Polymenis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3305459?pdf=render

Internet

http://europepmc.org/articles/PMC3305459?pdf=render

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