Epigenetic Analysis of Circulating Tumor DNA in Localized and Metastatic Prostate Cancer: Evaluation of Clinical Biomarker Potential

Epigenetic Analysis of Circulating Tumor DNA in Localized and Metastatic Prostate Cancer: Evaluation of Clinical Biomarker Potential

Novel and minimally-invasive prostate cancer (PCa)-specific biomarkers are needed to improve diagnosis and risk stratification. Here, we investigated the biomarker potential in localized and <i>de novo</i> metastatic PCa (mPCa) of methylated circulating tumor DNA (ctDNA) in plasma. Using...

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Bibliographic Details
Main Authors: Marianne Trier Bjerre, Maibritt Nørgaard, Ole Halfdan Larsen, Sarah Østrup Jensen, Siri H. Strand, Peter Østergren, Mikkel Fode, Jacob Fredsøe, Benedicte Parm Ulhøi, Martin Mørck Mortensen, Jørgen Bjerggaard Jensen, Michael Borre, Karina D. Sørensen
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
prostatic neoplasms
DNA methylation
liquid biopsy
circulating tumor DNA
biomarkers
Online Access:https://www.mdpi.com/2073-4409/9/6/1362

Internet

https://www.mdpi.com/2073-4409/9/6/1362

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