Astragaloside IV Stimulates Angiogenesis and Increases Nitric Oxide Accumulation via JAK2/STAT3 and ERK1/2 Pathway

Astragaloside IV (AS-IV), one of the major active constituents of Astragalus membranaceus in Traditional Chinese Medicine, has been widely used to treat ischemic diseases. However, the potential mechanism is this action is unclear. In this study, we tested the hypothesis that AS-IV might promote ang...

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Bibliographic Details
Main Authors: Xiao-Hu Chen, Jian-Dong Chen, Shi-Guang Wang, Yan Xu, Chuan-Hua Yang
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/10/12809