Colonic Motility and Jejunal Vagal Afferent Firing Rates Are Decreased in Aged Adult Male Mice and Can Be Restored by an Aminosterol

There is a general decline in gastrointestinal function in old age including decreased intestinal motility, sensory signaling, and afferent sensitivity. There is also increased prevalence of significant constipation in aged populations. We hypothesized this may be linked to reduced colonic motility...

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Bibliographic Details
Main Authors: Christine L. West, Jessica Y. Amin, Sohana Farhin, Andrew M. Stanisz, Yu-Kang Mao, Wolfgang A. Kunze
Format: Article
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neuroscience
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