Toll-like receptor 2 induced angiogenesis and invasion is mediated through the Tie2 signalling pathway in rheumatoid arthritis.

<h4>Background</h4>Angiogenesis is a critical early event in inflammatory arthritis, facilitating leukocyte migration into the synovium resulting in invasion and destruction of articular cartilage and bone. This study investigates the effect of TLR2 on angiogenesis, EC adhesion and invas...

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Bibliographic Details
Main Authors: Tajvur Saber, Douglas J Veale, Emese Balogh, Jennifer McCormick, Sinead NicAnUltaigh, Mary Connolly, Ursula Fearon
Format: Article
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
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