Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report

Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report

Abstract Background Pancreatic adenosquamous carcinoma has a poor prognosis, with limited prospective trial data to guide optimal treatment. The potential impact of drug metabolism on the treatment response of patients with pancreatic adenosquamous carcinoma is largely unknown. Case presentation We...

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Bibliographic Details
Main Authors: Claire M. Connell, Rebecca Brais, Hayley Whitaker, Sara Upponi, Ian Beh, Jane Risdall, Pippa Corrie, Tobias Janowitz, Duncan I. Jodrell
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Cancer
Subjects:
Cytidine deaminase
Drug metabolism
Gemcitabine
Pancreatic adenosquamous carcinoma
Online Access:https://doi.org/10.1186/s12885-020-6516-1

Internet

https://doi.org/10.1186/s12885-020-6516-1

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