Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis.

hTTLL12 is a member of the tubulin tyrosine ligase (TTL) family that is highly conserved in phylogeny. It has both SET-like and TTL-like domains, suggesting that it could have histone methylation and tubulin tyrosine ligase activities. Altered expression of hTTLL12 in human cells leads to specific c...

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Main Authors: Jan Brants, Kostyantyn Semenchenko, Christine Wasylyk, Aude Robert, Annaick Carles, Alberto Zambrano, Karine Pradeau-Aubreton, Catherine Birck, Jack A Schalken, Olivier Poch, Jan de Mey, Bohdan Wasylyk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3520985?pdf=render