HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex.

The tumor necrosis factor receptor (TNFR) superfamily mediates signals critical for regulation of the immune system. One family member, CD40, is important for the efficient activation of antibody-producing B cells and other antigen-presenting cells. The molecules and mechanisms that mediate CD40 sig...

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Bibliographic Details
Main Authors: Bruce S Hostager, Daniel K Fox, Douglas Whitten, Curtis G Wilkerson, Betty A Eipper, Victor P Francone, Paul B Rothman, John D Colgan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2894856?pdf=render