Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege.

Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege.

The testis is an organ with immune privilege. The comprehensive blood-testis barrier formed by Sertoli cells protects autoimmunogenic spermatozoa and spermatids from attack by the body's immune system. The interleukin (IL)-6/IL-12 family cytokines IL-12 (p35/p40), IL-23 (p19/p40), IL-27 (p28/Ep...

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Bibliographic Details
Main Authors: Hayato Terayama, Takayuki Yoshimoto, Shuichi Hirai, Munekazu Naito, Ning Qu, Naoyuki Hatayama, Shogo Hayashi, Kana Mitobe, Jun-Ichi Furusawa, Izuru Mizoguchi, Takeshi Kezuka, Hiroshi Goto, Kaori Suyama, Hiroshi Moriyama, Kou Sakabe, Masahiro Itoh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3997559?pdf=render

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http://europepmc.org/articles/PMC3997559?pdf=render

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