Evaluation of the immunomodulatory effects of cobalt, copper and magnesium ions in a pro inflammatory environment

Abstract Biomaterials and scaffolds for Tissue Engineering are widely used for an effective healing and regeneration. However, the implantation of these scaffolds causes an innate immune response in which the macrophage polarization from M1 (pro-inflammatory) to M2 (anti-inflammatory) phenotype is c...

Full description

Bibliographic Details
Main Authors: Leire Díez-Tercero, Luis M. Delgado, Elia Bosch-Rué, Roman A. Perez
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91070-0