Impact of Gentamicin Concentration and Exposure Time on Intracellular Yersinia pestis

The study of intracellular bacterial pathogens in cell culture hinges on inhibiting extracellular growth of the bacteria in cell culture media. Aminoglycosides, like gentamicin, were originally thought to poorly penetrate eukaryotic cells, and thus, while inhibiting extracellular bacteria, these ant...

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Bibliographic Details
Main Authors: Tiva T. VanCleave, Amanda R. Pulsifer, Michael G. Connor, Jonathan M. Warawa, Matthew B. Lawrenz
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00505/full