Characterization of Hypoxia Signature to Evaluate the Tumor Immune Microenvironment and Predict Prognosis in Glioma Groups

Characterization of Hypoxia Signature to Evaluate the Tumor Immune Microenvironment and Predict Prognosis in Glioma Groups

Glioma groups, including lower-grade glioma (LGG) and glioblastoma multiforme (GBM), are the most common primary brain tumor. Malignant gliomas, especially glioblastomas, are associated with a dismal prognosis. Hypoxia is a driver of the malignant phenotype in glioma groups; it triggers a cascade of...

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Bibliographic Details
Main Authors: Wanzun Lin, Shihong Wu, Xiaochuan Chen, Yuling Ye, Youliang Weng, Yuhui Pan, Zhangjie Chen, Long Chen, Xianxin Qiu, Sufang Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
hypoxia
gene set enrichment analysis
tumor microenvironment
hypoxia risk model
glioma
immune response
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00796/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00796/full

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