Variables that influence BRAF mutation probability: A next-generation sequencing, non-interventional investigation of BRAFV600 mutation status in melanoma.

The incidence of melanoma, particularly in older patients, has steadily increased over the past few decades. Activating mutations of BRAF, the majority occurring in BRAFV600, are frequently detected in melanoma; however, the prognostic significance remains unclear. This study aimed to define the pro...

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Bibliographic Details
Main Authors: Maria Rita Gaiser, Alexander Skorokhod, Diana Gransheier, Benjamin Weide, Winfried Koch, Birgit Schif, Alexander Enk, Claus Garbe, Jürgen Bauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5703505?pdf=render