Dynamic control of the dopamine transporter in neurotransmission and homeostasis

Abstract The dopamine transporter (DAT) transports extracellular dopamine into the intracellular space contributing to the regulation of dopamine neurotransmission. A reduction of DAT density is implicated in Parkinson’s disease (PD) by neuroimaging; dopamine turnover is dopamine turnover is elevate...

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Bibliographic Details
Main Authors: Mengfei Bu, Matthew J. Farrer, Habibeh Khoshbouei
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00161-2