T-Regulatory Cells and Vaccination “Pay Attention and Do Not Neglect Them”: Lessons from HIV and Cancer Vaccine Trials

Efficient vaccines are characterized by the establishment of long-lived memory T cells, including T-helper (effectors and follicular) and T-regulatory cells (Tregs). While the former induces cytotoxic or antibody responses, the latter regulates immune responses by maintaining homeostasis. The role o...

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Bibliographic Details
Main Authors: Vedran Brezar, Véronique Godot, Liang Cheng, Lishan Su, Yves Lévy, Nabila Seddiki
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Vaccines
Subjects:
HIV
Online Access:http://www.mdpi.com/2076-393X/4/3/30