PKC Regulates YAP Expression through Alternative Splicing of YAP 3′UTR Pre-mRNA by hnRNP F

The Yes-associated protein (YAP) is a transcriptional co-activator that plays critical roles in organ development and tumorigenesis, and is verified to be inhibited by the Hippo signaling pathway. In the present study, we show that the YAP 3′UTR is alternatively spliced to generate a novel 950 bp 3′...

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Bibliographic Details
Main Authors: Wing-Keung Chu, Li-Man Hung, Chun-Wei Hou, Jan-Kan Chen
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
PKC
Online Access:https://www.mdpi.com/1422-0067/22/2/694