Influence of Anesthesia and Clinical Variables on the Firing Rate, Coefficient of Variation and Multi-Unit Activity of the Subthalamic Nucleus in Patients with Parkinson’s Disease

Influence of Anesthesia and Clinical Variables on the Firing Rate, Coefficient of Variation and Multi-Unit Activity of the Subthalamic Nucleus in Patients with Parkinson’s Disease

Background: Microelectrode recordings (MER) are used to optimize lead placement during subthalamic nucleus deep brain stimulation (STN-DBS). To obtain reliable MER, surgery is usually performed while patients are awake. Procedural sedation and analgesia (PSA) is often desirable to improve patient co...

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Bibliographic Details
Main Authors: Michael J. Bos, Ana Maria Alzate Sanchez, Raffaella Bancone, Yasin Temel, Bianca T.A. de Greef, Anthony R. Absalom, Erik D. Gommer, Vivianne H.J.M. van Kranen-Mastenbroek, Wolfgang F. Buhre, Mark J. Roberts, Marcus L.F. Janssen
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Journal of Clinical Medicine
Subjects:
deep brain stimulation
microelectrode recordings
subthalamic nucleus
procedural sedation and analgesia
Parkinson’s disease
clonidine
Online Access:https://www.mdpi.com/2077-0383/9/4/1229

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https://www.mdpi.com/2077-0383/9/4/1229

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