Natural and vaccine-mediated immunity to Salmonella Typhimurium is impaired by the helminth Nippostrongylus brasiliensis.

BACKGROUND:The impact of exposure to multiple pathogens concurrently or consecutively on immune function is unclear. Here, immune responses induced by combinations of the bacterium Salmonella Typhimurium (STm) and the helminth Nippostrongylus brasiliensis (Nb), which causes a murine hookworm infecti...

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Bibliographic Details
Main Authors: Saeeda Bobat, Matthew Darby, Dunja Mrdjen, Charlotte Cook, Erin Logan, Jennifer Auret, Elizabeth Jones, Corinna Schnoeller, Adriana Flores-Langarica, Ewan A Ross, Alykhan Vira, Constantino López-Macías, Ian R Henderson, James Alexander, Frank Brombacher, William G Horsnell, Adam F Cunningham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4256288?pdf=render