NASH-related increases in plasma bile acid levels depend on insulin resistance

NASH-related increases in plasma bile acid levels depend on insulin resistance

Background & Aims: Plasma bile acids (BAs) have been extensively studied as pathophysiological actors in non-alcoholic steatohepatitis (NASH). However, results from clinical studies are often complicated by the association of NASH with type 2 diabetes (T2D), obesity, and insulin resistance (...

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Main Authors: Guillaume Grzych, Oscar Chávez-Talavera, Amandine Descat, Dorothée Thuillier, An Verrijken, Mostafa Kouach, Vanessa Legry, Hélène Verkindt, Violeta Raverdy, Benjamin Legendre, Robert Caiazzo, Luc Van Gaal, Jean-Francois Goossens, Réjane Paumelle, Sven Francque, François Pattou, Joel T. Haas, Anne Tailleux, Bart Staels
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:JHEP Reports
Subjects:
NASH
NAFLD
Bile acids
Diabetes
Insulin resistance
Obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555920301567

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http://www.sciencedirect.com/science/article/pii/S2589555920301567

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