Neural substrate of cold-seeking behavior in endotoxin shock.

Systemic inflammation is a leading cause of hospital death. Mild systemic inflammation is accompanied by warmth-seeking behavior (and fever), whereas severe inflammation is associated with cold-seeking behavior (and hypothermia). Both behaviors are adaptive. Which brain structures mediate which beha...

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Bibliographic Details
Main Authors: Maria C Almeida, Alexandre A Steiner, Luiz G S Branco, Andrej A Romanovsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762328?pdf=render