Comparison of Genetic Profiling between Primary Tumor and Circulating Tumor Cells Captured by Microfluidics in Epithelial Ovarian Cancer: Tumor Heterogeneity or Allele Dropout?

Comparison of Genetic Profiling between Primary Tumor and Circulating Tumor Cells Captured by Microfluidics in Epithelial Ovarian Cancer: Tumor Heterogeneity or Allele Dropout?

Epithelial ovarian cancer (EOC) is a leading cause of cancer mortality among women but unfortunately is usually not diagnosed until advanced stage. Early detection of EOC is of paramount importance to improve outcomes. Liquid biopsy of circulating tumor cells (CTCs) is emerging as one of the promisi...

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Bibliographic Details
Main Authors: Ting-Yu Chang, Sheng-Wen Chen, Wen-Hsiang Lin, Chung-Er Huang, Mark I. Evans, I-Fang Chung, Janne-Wha Wu, Gwo-Chin Ma, Ming Chen
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Diagnostics
Subjects:
EOC
CTC
liquid biopsy
whole exome sequencing
tumor heterogeneity
allele dropout
Online Access:https://www.mdpi.com/2075-4418/11/6/1102

Internet

https://www.mdpi.com/2075-4418/11/6/1102

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