Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer

<p>Abstract</p> <p>Background</p> <p>Thromboxane synthase (TXS) metabolises prostaglandin H2 into thromboxanes, which are biologically active on cancer cells. TXS over-expression has been reported in a range of cancers, and associated with a poor prognosis. TXS inhibiti...

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Bibliographic Details
Main Authors: O'Byrne Kenneth J, Kay Elaine, Cummins Robert, Gately Kathy, Cathcart Mary-Clare, Pidgeon Graham P
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/25