Is replication the gold standard for validating genome-wide association findings?

With the advent of genome-wide association (GWA) studies, researchers are hoping that reliable genetic association of common human complex diseases/traits can be detected. Currently, there is an increasing enthusiasm about GWA and a number of GWA studies have been published. In the field a common pr...

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Bibliographic Details
Main Authors: Yong-Jun Liu, Christopher J Papasian, Jian-Feng Liu, James Hamilton, Hong-Wen Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2605260?pdf=render