Improving promiscuous mammalian cell entry by the baculovirus Autographa californica multiple nuclear polyhedrosis virus

Improving promiscuous mammalian cell entry by the baculovirus Autographa californica multiple nuclear polyhedrosis virus

The insect baculovirus AcMNPV (Autographa californica multiple nuclear polyhedrosis virus) enters many mammalian cell lines, prompting its application as a general eukaryotic gene delivery agent, but the basis of entry is poorly understood. For adherent mammalian cells, we show that entry is favoure...

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Bibliographic Details
Main Authors: Neil M. J. O’Flynn, Avnish Patel, Jan Kadlec, Ian M. Jones
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2012-11-01
Series:Bioscience Reports
Subjects:
baculovirus
fusion
gene transduction
gp64
mammalian cell
virus entry
Online Access:http://www.bioscirep.org/bsr/033/e003/bsr033e003.htm

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http://www.bioscirep.org/bsr/033/e003/bsr033e003.htm

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