CD49b/CD69-dependent generation of resting T helper cell memory

In the absence of antigen, memory T helper (Th) cells are maintained in a resting state. Recently it has been shown that bone marrow (BM) is a major reservoir of resting memory Th cells. In a given immune response, less than 10% of the activated CD4 T cells are recruited to the pool of resting BM me...

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Bibliographic Details
Main Authors: Asami eHanazawa, Max eLöhning, Andreas eRadbruch, Koji eTokoyoda
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00183/full